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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '351ac5cb0662f023509557159cbb20faca8019f2f29b8353584eb273e33d279e' 
  AND token = 'gP4iS7Ad8KwlcD5RmW8cUnfCYU4zTieYZaEKkz2Xc9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}