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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '380b50bce9d3ddd9e6c308e0d1e5f703b36c044e95b910976e668e54a8c73c75' 
  AND token = 'BtCo7MxtlKFeMCkLT+QzLzCSZfegRWTUGOmozro0fEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}