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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22a077d62a16a46aa82d53b5d007bf465df1b52a94df25ddd0c768884952fa67' 
  AND token = '9GJZIMCAuAVmSvzKHWzkd0EF6EnxPqDxrd2AtOXe6/s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}