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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465277f95005eb4aa97adb2267b3b5ae793c8ba61c28a3e615633c02548bb4ba' 
  AND token = 'PXy5ybQ0yi93XW644JYCoBdayq3tQsOhGpFBRnmYdpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}