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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d4c13835ea7e10b4b3c6ca3231a407b504e73ab3666c566f2fa0d59f39b106' 
  AND token = 'OPoZY5GbDHNUWbkaXJgql075BJIu7RX43kfqfJ7Lf1I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}