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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae6606f6c2d1424bd316ae3508bf71f3005910432a6cc8e816faf539ff6c4de1' 
  AND token = 'PXvBloQZr/2sq/KDHDivdY/TRn9S0D7AB0bSuQ3pOWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}