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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '281f7a01de3d29aae86c2333a018ee500088159d5097eb60d74597c0d32f89a1' 
  AND token = '/4ocvcpqJHc4M5u6gtjPj71tkMnoa5Ti3RHzanGeytI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}