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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '644b9afe2896574d117fbe6f54b0cb11cb18296b3d9b0c8df4ed84186bf5022d' 
  AND token = 'uwjZ/MBXba2ZlQVWyzn9Z5geb/B5dPdISBbexDrcKfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}