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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b116467fb75af078851769614f4cda1e0c3d3c8b6b075200fcf94ab4907c184' 
  AND token = '6EQ8ex0rqGpRmYYa93WSiL9iag56I2jwMe5KIcndvpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}