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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24f4cf745648b6e935911367f4a387705a349349d26b25517fa371ccc5e4147b' 
  AND token = 'X/WuoA7EUEQJTDbW2OT894P/LVjQlrbhLJLOl3RXWrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}