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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '042e2f3da26f7070fcd68798d774a3f7eba02e2cbe0986c02e78357d786ef91b' 
  AND token = 'UO8sF1e/VBQPGAW1A2okV3Yx2K2QvN8oVJn3UgK67aQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}