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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b66416a76c21de5d991f46e876a140478d64bb82ef0beba39390a0b45f2ab841' 
  AND token = '49Gfb5i8rvklGEaqD6t3bgvSAGLqc8TKCuRSb+tjI5s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}