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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9ac3afdd9ae2ade7e7e23b5edcdc2853af1ef7f451d3af40b26387ff502f894' 
  AND token = '8p3+gStIU8lAfXc4/qTlkHcC3vSYHDIEhSRdCfiOpBw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}