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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b2ad8e634bd7583de87c300a6961f966feecb054717bb068bb46bcf6fd20bc6' 
  AND token = 'p6TQhyDA/HrkFLtjTGXO5clWU8pjjDyD30YPq7hvUA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}