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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f449d85729901163367f4dc88a7fb74b00b44f65750343c8b275aa504674d308' 
  AND token = 'U86kV0IfklJLCtuq11BY82pBrEJP5WsLAZ5pk+L4/Dg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}