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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0a9ca141fe93ab7e245a8a7bed418326107be40fcb65301ce5aae05dc6c6d8' 
  AND token = 'pwqObuTkCiYv03uuL77dzV4iQez/HHhc2U0eTv25nig=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}