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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43bde1c8db25fc7cb2d8d6b9375ea31584a9ffbc39f3572a4fd60ebcf9ece8a6' 
  AND token = 'yp9ZAQf6my1os9kzMdmbnay44kn/B7TxxcfYcD9JSis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}