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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '980e0900e1146f632d7b7791f322e32f5b7241d43709c473288585b0420c2afd' 
  AND token = 'g3L2VX8sBLM/VWQhgTcvQxN+FsWSqAV/yxxNXUoZxeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}