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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6afc2ad8faa6a74093968cfb8bc53fc3cc1929f8e011e3748424591f4bf92465' 
  AND token = 'jpJQRP0fz+ajgKlb44smEbWKeS3blf8VEToMBKwtVt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}