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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fe869d04dcb166681d7f5fd99d8d03a78bffed344bf1aa5fd0f7bae3c21c16b0' 
  AND token = 'KGYmwwrPm9OMKoCAZSZvcenHa8tV0PYGNOCfBZQRHZA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}