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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4400486fc94da254de212a08b28054c3f533f7207b56490756376a15028b9c42' 
  AND token = 'jim30+J8178MfRD0qZg7U2kV9WBu2nznZWAWm7xwGng=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}